Buy Januvia Generic

What is Januvia?

Oral Januvia treats type 2 diabetes. Type 1 diabetes and diabetic ketoacidosis contraindicate it (increase in acid levels of the body in patients with uncontrolled diabetes). Januvia is sitagliptin. Merck makes 25 mg, 50 mg, and 100 mg versions. The three Januvia tablets are round film-coated tablets with different colors and codes. Pink, light beige, and beige pills with "221," "112," and "277" printed on them are 25 mg, 50 mg, and 100 mg, respectively.

Januvia is prescribed with diet and exercise. Sitagliptin is given with metformin if blood sugar levels remain uncontrolled. Those who need metformin plus sitagliptin can take Janumet and Janumet XR. Januvia is usually given once a day, although dosage depends on patient response.

How does Januvia work?

Januvia (sitagliptin) is a DPP-4 inhibitor. Januvia works twice. The pancreas produces more insulin. It lowers liver glucose overproduction. Januvia normalizes glucose and insulin levels. Januvia suppresses DPP-4 to meet these goals. DPP-4 destroys GLP and glucose-dependent insulinotropic polypeptide (GIP) (GIP). Post-meal intestinal GLP-1 and GIP release. Hormones release insulin. Hepatic glucagon suppression by GLP-1 lowers blood glucose. Glucagon produces glucose. Sitagliptin inhibits DPP-4, boosting insulin and reducing glucagon and glucose.

Januvia Side Effects

Most people taking Januvia do not experience any serious side effects. Some commonly reported side effects are:

• Headaches
• Upper respiratory tract infections
• Nausea
• Abdominal pain
• Diarrhea

Some rare but serious side effects with Januvia are:

• Pancreatitis (severe abdominal/back pain, loss of appetite, and persistent nausea/vomiting are signs of pancreatitis, which Januvia contraindicates)
• Nephropathy
• bullous pemphigoid
• Heart failure

Sitagliptin allergies are uncommon. Allergic responses cause rashes, itching, swelling of the face, tongue, or throat, confusion, and problems breathing or swallowing.

Severe adverse effects or allergic reactions require drug discontinuation and medical attention.

author: Harry, RPH